Title : From conception to perfection: An historical overview of IVF and embryo transfer
Abstract:
The realm of gynecology and women's healthcare plays a pivotal role in addressing the distinct healthcare needs of women across various life stages. In 1940, the maternal mortality rate in the United States stood at 363.9 maternal deaths per 100,000 live births, marking one of the most remarkable healthcare advancements in the latter half of the 20th century. Gynecologists specialize in a range of reproductive and gynecological issues, including family planning, infertility, and prenatal services. Within diagnostic techniques, gynecologists can identify and manage conditions such as polycystic ovary syndrome (PCOS), endometriosis, and uterine fibroids. Tailoring treatment plans to individual patient needs, the field of assisted reproductive technology (ART) has witnessed significant progress since the birth of Louise Brown, the first "test-tube baby," through IVF in 1978. This technology has proliferated globally, with clinics and researchers refining the process. Advancements include the development of sophisticated culture media enhancing embryo development, the introduction of Intracytoplasmic Sperm Injection (ICSI) revolutionizing male infertility treatment, and Preimplantation Genetic Testing (PGT) for screening chromosomal abnormalities and genetic disorders before embryo transfer. The shift towards Single Embryo Transfer (SET) aims to reduce the risk of multiple pregnancies and enhance overall success rates. Ongoing research explores Mitochondrial Replacement Therapy (MRT) for addressing mitochondrial disorders in embryos. The dynamic nature of the field is underscored by continuous research and developments that shape the future of assisted reproductive technologies. It is crucial to acknowledge the evolving landscape of ethical considerations, legal regulations, and societal perspectives alongside technological advancements in IVF.
Keywords: IVF, ART, Embryo Transfer, gynecological issues
Audience Take Away:
- Insight into the historical development of in vitro fertilization (IVF) and embryo transfer.
- Overview of how ART has evolved globally, with a focus on the refinements made by clinics and researchers in the IVF process.
- Insight into how diagnostic techniques enhance the selection and viability of embryos.
- Understanding how advancements in imaging contribute to better decision-making in the IVF process.
- Exploration of advancements in understanding the uterine environment, leading to improved timing for embryo transfer based on endometrial receptivity.
