Infections of the urogenital tract are often convicted in 15% of the cases of infertility in females. The microorganisms present in vagina play an important role in determining several aspects of reproductive health. However, well designed studies on infections and infertility ar [....] » Read More
The study shows peritoneal metaplastic conversion to normal vagina by LPV. The progenitor cell responsible for the metaplastic conversion was identified in the peritoneum and different stages of neo?vaginal development. The translational stemness markers NANOG, OCT4, and SOX2 res [....] » Read More
Transplantation of organs is a rapidly expanding faculty of medicine. While the solid organ transplantation has grown by leaps and bounds, ovarian transplantation is still in its infancy. Although recent interest has been generated for preservation of fertility in cancer therapy [....] » Read More
Background: Polycystic Ovary Syndrome (PCOS) is among the most prevalent endocrine disorders affecting reproductive-age females, with a global prevalence of 6-10%. It is characterized by hyperandrogenism, ovulatory dysfunction, and/or the presence of polycystic ovaries. Common cl [....] » Read More
Background: Delivery by Cesarean section (c-section) is a common procedure, and it has well-documented risks for the mother and the neonate. This mode of delivery is associated with maternal mortality and morbidity due to hemorrhage and thromboembolisms, as well as increased labo [....] » Read More
Successful pregnancy is critically dependent on the placenta, a transient yet highly specialized organ governed by intricate, dynamic gene regulatory networks. Disruption of these intercellular and intracellular programs can lead to a range of pregnancy complications and fetal de [....] » Read More
Women represents 50% of the population globally and 80% of purchasing decisions in healthcare are made by women. It is a common knowledge that women feel a pressure to be a “superwoman”- women feel the pressure to manage and juggle across all aspects of their life(inc [....] » Read More
Gestational Diabetes Mellitus (GDM) is one of the most common pregnancy complications and is associated with significant maternal and neonatal morbidity. Beyond the well-established risk of foetal overgrowth, increasing evidence suggests that GDM may induce subtle cardiovascular [....] » Read More
Background: Outpatient hysteroscopy is an invaluable tool for investigations and management of postmenopausal bleeding. Since June 2021 University Hospital Waterford runs a “one-stop-shop” where women have an ultrasound, a hysteroscopy, biopsy or removal of polyp if i [....] » Read More
Introduction: Various degrees of damage to the perineum and vaginal opening are common after vaginal delivery. These deformities can be either natural or post-traumatic. The above-mentioned causes result in complaints like discomfort during sexual intercourse, vaginal drynes [....] » Read More
Chronic endometritis is a chronic long–term disease of the endometrium, accompanied by inflammation and causing such pathologies of the reproductive system as menstrual irregularities, infertility and miscarriage. Because of the widespread prevalence of chronic endometri [....] » Read More
Sexual dysfunction is a common clinical condition due to different causes including the use of selective serotonin reuptake inhibitors (SSRIe). Paroxetine, which is one of the SSRIs, is known to cause sexual dysfunction including erectile dysfunction in men. Asprosin, released fr [....] » Read More
Background: Hyperprolactinemia is associated with hypogonadism and estrogen deficiency, both of which are known contributors to bone mineral density (BMD) loss. While osteoporosis is well established in hyperprolactinemia, little is known about its prevalence in macroprolactinemi [....] » Read More
The integration of thread technology into gynecological practice represents a significant advancement in both aesthetic and functional treatment modalities. Originally utilized in dermatology for facial rejuvenation, absorbable threads such as polydioxanone (PDO), poly-L-lactic a [....] » Read More
Endometriosis affects approximately 10% of women worldwide, causing significant pains, infertility, and reduced quality of life. Despite its prevalence, the condition is notoriously underdiagnosed, with an average delay of 7-10 years between symptom onset and diagnosis. Current d [....] » Read More
Recurrent pregnancy loss (RPL), defined as the loss of two or more consecutive pregnancies, is a multifactorial condition influenced by both maternal and paternal factors. While maternal causes are extensively studied, male factors, including alterations in semen quality, sperm D [....] » Read More
During pregnancy the haemostatic system is progressively activated to prepare the haemostatic needs of delivery and postpartum. Blood hypercoagulability, endothelial injury and stasis of blood flow predispose to thrombus formation. Pulmonary embolism is a complication of venous t [....] » Read More
Vulvovaginal Congenital Anomalies affects both genital tract health as well as fertility and reproduction. External genitalia should be checked in any case immediately after delivery. Amenorrhea, oligomenorhea and pelvic pain are common symptoms of lower genital tract congenital [....] » Read More
Sexual assault is a deeply traumatic experience with far-reaching physical, emotional, and psychological effects. Gynecologists often serve as critical points of contact for survivors, providing care that extends beyond medical treatment to encompass emotional support and advocac [....] » Read More
Purpose: An exposure to bodily fluid can happen very quickly—in just one blink of an eye a person can be exposed to bodily fluids. Thus creating a life-changing experience for the rest of that person’s life. During the procedure of inserting an IV, the pat [....] » Read More
Obesity is a global epidemic resulting in multiple medical co-morbidities and excessive consumption of health care resources. It is a medical condition caused by lifestyle, diet, metabolic dysfunction, genetic and socioeconomic factors, whose prevalence has risen dramatically ove [....] » Read More
Over the past century, societal shifts have significantly changed women’s role, particularly those who wish to have children. If we fail to recognize and address the challenge women face in balancing professional ambitions with family life, fertility rates will likely remai [....] » Read More
Pelvic floor Dysfunction (PFD) is a highly prevalent condition affecting nearly half of parous women by the age of 80. Despite the widespread use of vaginal pessaries as a conservative treatment, limitations in current designs — including poor anatomical fit, discomfort, hy [....] » Read More
Objective: To highlight a rare but serious complication of uterine artery embolization—sepsis secondary to infected necrotic fibroid tissue—and to emphasize the importance of early recognition, multidisciplinary management, and appropriate follow-up in post-UAE patien [....] » Read More
Context: Chronic pelvic pain in women is defined as intermittent or constant pain in the lower abdomen or pelvis for six months or more and affects more than 24% of women worldwide. National recommendations from the United Kingdom, Japan, the United States, and Canada recom [....] » Read More
Background: Laparoscopic ovarian cystectomy is a well-established treatment for benign ovarian cysts in women of reproductive age. However, surgical intervention may affect ovarian reserve by disrupting ovarian tissue or vascularization. Increasing attention has focused on whethe [....] » Read More
Objective: To establishment of an ideal animal model of POP and the mechanism of action of POP-related extracellular matrix proteins on the occurrence, development and reversal of POP. Method: Thirty-six SD rats (female, 500-550g) were selected and after one month of adap [....] » Read More
Objective: To compare the efficacy evaluation of three kinds of treatment for adenomyosis and to discuss the application prospect of radiofrequency ablation for adenomyosis. Method: The clinical data of 180 patients with adenomyosis were retrospectively analyzed, including 75 [....] » Read More
Background: Triple-negative breast cancer (TNBC) is a particularly aggressive type of breast cancer, known for its lack of effective treatments and unfavorable prognosis. The G protein-coupled estrogen receptor (GPER), a novel estrogen receptor, is linked to increased malignancy [....] » Read More
Cancer immunotherapy could eradicate cancer and prevent recurrence by augmenting the natural ability of the immune system. Cancer immunotherapy alone or in combination with surgery, radiotherapy, chemotherapy, anti–vascular EGF (VEGF) therapy, and regulatory T cell (Treg)-t [....] » Read More
Objectives: Inflammation is a hallmark of HPV-mediated cervical cancer; Matrix metalloproteinase [MMP]-2 and tissue inhibitor of metalloproteinase [TIMP]-2 are emerging as pivotal players in inflammation and carcinogenesis. My study aimed to evaluate the role of MMP-2 (-735C>T [....] » Read More
Objective: L1 cell adhesion molecule (L1CAM) has emerged as a potential prognostic biomarker in endometrial cancer. This systematic review and meta-analysis aimed to comprehensively evaluate the prevalence of L1CAM expression across molecular subtypes of endometrial cancer and it [....] » Read More
The embryo transfer is one of the key steps in IVF. While the procedure itself is relatively simple, the success of embryo implantation can be influenced by a range of factors. One of the most significant is the embryo expulsion. This phenomenon is the result of uterine con [....] » Read More
Objective: Endometriosis is a chronic disease of the female reproductive system, and is one of the causes of chronic pain and infertility in women of fertility age. This paper aims to investigate the relationship between the type and severity of pain and the level of the Anti-Mul [....] » Read More
Introduction: Short-interval pregnancy (SIP) is defined as an interval of fewer than 18 months between delivery and subsequent conception. It is associated with adverse maternal and fetal outcomes, and significant nationwide costs. Placement of long-acting reversible contraceptiv [....] » Read More
This case describes a 25-year-old African American woman (G1P0) with a medical history including a prior brain arteriovenous malformation (AVM) repair, pneumonia, and a urinary tract infection, who was admitted at 39 weeks gestation for labor and delivery. She underwent a spontan [....] » Read More
Background: Ectopic pregnancies account for approximately 2% of reported pregnancies (ACOG PB 193). Diagnosis relies on ultrasound imaging and trends of beta human chorionic gonadotropin levels. We present, to our knowledge, one of the first case reports of a ruptured tubal ect [....] » Read More
Intro. Endometriosis and connective tissue disorders are two under-researched and under- diagnosed chronic conditions with overlapping symptomologies and patient demographics. Women with endometriosis and hypermobile Ehlers-Danlos syndrome (hEDS; a genetic connective tissue dis [....] » Read More
Background: Intrauterine devices (IUD’s) are one of the most effective contraceptives to prevent unintended pregnancies; however, pain during insertion serves as a significant barrier to uptake. This study explores the clinical practices of California healthcare providers r [....] » Read More
Objective: To investigate the effect of preconception antioxidant nutrients on motile sperm concentration (MSC) after three months of supplementation in men with low baseline MSC who are trying to conceive at home. Materials and Methods: Participants with a low-normal MSC rang [....] » Read More
Background: Caesarean delivery is a common surgical intervention, but it carries a risk of surgical site infection (SSI), which can negatively affect maternal health, prolong hospital stay, and increase healthcare costs. Data from Northeastern Nigeria on SSI incidence and risk fa [....] » Read More
Background: Herpes simplex virus (HSV) vulvitis is typically self-limiting but may present severely in immunocompromised individuals. This case highlights an unusual presentation of HSV-1 vulvitis complicated by sepsis in the context of poorly controlled type 1 diabetes mell [....] » Read More
In recent years, the increasing number of pregnant women with comorbid mental disorders has become a major concern. Without appropriate support, their physical and mental health, as well as that of their fetuses and newborns, may be adversely affected. Breastfeeding is crucial fo [....] » Read More
This study aims to clarify the content of instruction and points to keep in mind regarding breastfeeding and co-sleeping, based on a survey of infant asphyxiation deaths caused by these practices. Over the past 10 years, 16 cases of infant asphyxiation due to sleeping and breastf [....] » Read More
Title : Understanding pelvic organ prolapse
Woojin Chong, NYU Langone Medical Center, United States
Pelvic Organ Prolapse (POP) is descent of one or more pelvic structures, from the normal anatomic position, usually to or beyond the hymenal remnants, owing to loss of support from the connective tissue, muscles, or both. It can lead to symptoms of pelvic pressure, vaginal bulge, [....] » Read More
Title : Eliminating suffering from breast cancer -The Lavender Way
Phillip Bretz, Visionary Breast Center, United States
Forty years ago we thought huge cancer institutions coupled with comprehensive cancer centers and mammography machines on every corner were the answer for breast cancer. It was not. The 43,000 plus women yearly who have gone through hell and then died are a testament to that. Des [....] » Read More
Title : Efficacy of full piers calculator in predicting adverse maternal outcomes in preeclampsia at a tertiary care hospital in South India
Sangeeta Shah, Govenment Medical College, India
Preeclampsia and other hypertensive disorders of pregnancy (HDPs) remain the leading causes of maternal and perinatal morbidity and mortality. The World Health Organization estimates that at least one woman dies every seven minutes from the complications of HDPs. The Preeclampsia [....] » Read More
Title : Treating breast cancer with the breast intact and the patient fully awake, has a lasting positive psychological impact aka The Lavender Way - Lavender procedure
Phillip Bretz, Visionary Breast Center, United States
Background: Our previous publication in RAS, Research Article: The Lavender Way - Lavender Procedure, a Way to Defeat Breast Cancer Without Surgery, Chemotherapy, or Radiation. A Clarion Call for Radical Change, did not detail what we consider to be an extremely valuable contribu [....] » Read More
Title : Investigation of OAS1, OAS3, and other differentially expressed genes in cervical cancer
Samantha Hsu, University of Central Florida College of Medicine, United States
Introduction: Cervical cancer (CC) is the fourth most common cancer among women, with approximately 604,000 new cases diagnosed annually worldwide. It is caused predominantly by high-risk strains of human papillomavirus (HPV), which inactivate tumor suppressor gene function. Adva [....] » Read More
Title : Demographic characteristics of women with uterine leiomyomas: A comparative analysis of the all of us research program participants
Saarah K Sherifi, The University of Central Florida College of Medicine, United States
Background. Uterine leiomyomas are the most common benign tumors in women of reproductive age, affecting approximately one in four women. Despite their high prevalence, the demographic and geographic prevalence trends remain understudied. Building on a prior Florida-based analy [....] » Read More
Title : ICD 10 Z Codes and social determinants of health in emergency department encounters for salpingitis and oophoritis
Cassandra Farber, Pennsylvania State College of Medicine, United States
Objective: This study characterized the demographic and clinical profile of patients with documented social determinants of health (SDOH) ICD-10 Z codes (Z55–Z65) who presented to the emergency department (ED) with salpingitis and oophoritis, and explores patterns of health [....] » Read More
Title : Impact of documented social determinants of health (ICD 10 Z Codes) on emergency department outcomes in ectopic pregnancy
Cassandra Farber, Pennsylvania State College of Medicine, United States
Objective: This study characterizes the demographic and clinical profile of patients with documented social determinants of health (SDOH) ICD-10 Z codes (Z55–Z65) presenting to the emergency department (ED) with ectopic pregnancy, and explores healthcare utilization and man [....] » Read More
Title : Patterns of maternal and infant healthcare utilization following prenatal substance use
Jessica Liu, Central Michigan University College of Medicine, United States
Background: Prenatal substance exposure to opioids, tobacco, and marijuana has been linked to adverse health outcomes in children. However, the relationship with early childhood medical service utilization remains underexplored, particularly in distinguishing between specific sub [....] » Read More
Title : Achieving the unconceived: Honing the power to conceive through reproductive crypt technologies
Anne Catherine Barrett Belanger, Fertility Business Initiatives Institute, United States
Objective: To evaluate the integration of the Billings Ovulation Method® as a first-line approach for subfertile couples and explore its role as a complementary patient-centered strategy for achieving natural conception prior to resorting to and initiating assisted reproducti [....] » Read More
Title : Comparing the efficacy of levonorgestrel intrauterine device and oral levonorgestrel for emergency contraception: A systematic review and meta analysis
Andie Blankenstein, Central Michigan University, United States
Background: Emergency contraception (EC) is critical for preventing unintended pregnancies following unprotected or inadequately protected sexual intercourse. While oral levonorgestrel (LNG) pills are the standard FDA-approved EC method, the levonorgestrel intrauterine devic [....] » Read More
Title : Breastfeeding influence on vaginal bleeding in late labor: A comparative study
Atiya Kareem Mohammed, University of Sulaimani, Iraq
Background: Losing blood in the labour's 3rd stage is the primary factor that impacts maternal health. Immediate breastfeeding could be considered a saving factor in the life of mothers. Since it could naturally spread the oxytocin to stimulate the uterine contraction, dislod [....] » Read More
Title : Investigating patients’ knowledge of clinical breast examinations
Sophia Fraga, University of Michigan Medical School, United States
Background: While clinical breast exams (CBEs) have long been a standard part of health maintenance visits, recent evidence questions their utility in resource-rich settings where mammography is readily available. Systematic reviews suggest that for every cancer detected by CBE, [....] » Read More
Title : Delivery modalities and challenges in cerebral palsy patients: A case study
Swati Kumari, BronxCare Hospital, United States
Cerebral palsy (CP) presents unique challenges during pregnancy and delivery due to associated motor impairments, comorbidities, and sensory deficits. As medical advancements increase the number of women with CP reaching childbearing age, tailored obstetric care becomes essential [....] » Read More
Title : Comparing in-person and phone translation services for spanish-speaking patients
Swati Kumari, BronxCare Hospital, United States
Effective communication is vital for high-quality patient care, especially for non-English-speaking populations. This study examines the impact of translation services on patient satisfaction and communication effectiveness, aiming to extend our impact on population and community [....] » Read More