Progestins are a type of hormone used to regulate the menstrual cycle and prevent pregnancy. They are synthetic versions of the hormone progesterone, which is naturally produced by the ovaries. Progestins work by preventing ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and thinning the lining of the uterus to prevent implantation of a fertilized egg. Progestins also help prepare the body for pregnancy by supporting the development of the endometrium, or inner lining of the uterus. Progestins are used in several forms of birth control, including the pill, the patch, and the ring. They are also used in hormone replacement therapy to treat menopausal symptoms, such as hot flashes and night sweats. Progestins are also used to treat menstrual irregularities, endometriosis, and breast or uterine cancer. Progestins are generally safe and well-tolerated, although some people may experience side effects such as headaches, breast tenderness, nausea, and weight gain. In rare cases, they can cause serious health problems, such as blood clots and stroke. It is important to speak with a healthcare provider to determine if progestins are right for you.
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