It has been abundantly obvious in recent years that epigenetic alteration is critical throughout both early and late oogenesis and spermatogenesis. In other circumstances, such as embryo development and growth, diseases, and X-chromosome inactivation and genomic imprinting, epigenetic alterations are also implicated. Epigenetic reprogramming is defined as any mitotic or meiotic change that does not result in a change in DNA sequence yet has a significant impact on embryonic development. In addition to requiring epigenetic modification to become the germline, primordial germ cells undergo a distinct wave of epigenetic reprogramming that most other lineages do not. During prenatal and postnatal development, both internal and external influences influence epigenetic alteration. Because all of the epigenetic modification pathways are unclear, mis reprogramming of these steps can be changed with the help of medications and nutrition if epigenetic modification is understood. Furthermore, epigenetic control is required for multicellular organisms' biological complexity, cloning, and assisted reproductive technology progeny production.