Amniocentesis is a prenatal diagnostic procedure in which a small amount of amniotic fluid is removed from a pregnant woman's uterus and analyzed. It is generally performed between the 15th and 20th weeks of gestation, and is commonly offered to women who are at high risk of having a baby with a genetic or chromosomal disorder. The amniotic fluid, which surrounds the fetus in the uterus, contains cells shed by the fetus that can be used for genetic testing. During the procedure, a needle is inserted through the abdomen and into the uterus. A small amount of amniotic fluid is then withdrawn and sent to a laboratory for analysis. The most common use of amniocentesis is to check for chromosomal abnormalities. The cells in the amniotic fluid are tested for extra or missing chromosomes, as well as for certain specific genetic disorders such as Down syndrome and cystic fibrosis. Amniocentesis can also be used to identify the sex of the fetus and to check for infection. In addition to providing useful information about the health of the fetus, amniocentesis can also be used to diagnose certain conditions that may require treatment before birth. For example, if an abnormal amount of alpha-fetoprotein (AFP) is found in the amniotic fluid, it may indicate that the baby has a neural tube defect such as spina bifida. Amniocentesis is generally considered safe, although there is a small risk of complications, including infection, miscarriage, or premature labor. It is important to discuss the risks and benefits of the procedure with your healthcare provider before deciding whether or not to have an amniocentesis.
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