An intraepithelial lesion (IEL) is an area of abnormal cells on the surface of an organ or tissue. It is usually found during a biopsy or other procedure and is usually a sign of a pre-cancerous or cancerous condition. In some cases, an IEL can be a benign (non-cancerous) condition. IELs are most commonly found on epithelial tissue, which is the thin layer of cells that lines the surface of organs, such as the skin, digestive tract, and reproductive organs. When an IEL is present in these organs, it is often an indication of a potential cancer. The diagnosis of an IEL begins with a biopsy, which involves removing a small sample of the affected tissue. This sample is then examined under a microscope to look for the abnormal cells. Other tests, such as imaging studies, may be used to help determine the extent of the IEL. Treatment for IELs varies depending on the type and extent of the lesion. In many cases, the lesion can be removed with a simple procedure. In some cases, additional treatment, such as chemotherapy or radiation therapy, may be necessary. IELs are an important sign of potential cancer, and early detection is key to successful treatment. If you have any concerns about an IEL, it is important to discuss them with your doctor.
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