For decades the endometrial cavity has been considered a sterile environment, but this belief has been challenged since the late 1950s. However, it is only from the beginning of the 2000s that it was possible to define the characteristics of the microbiota in the [....] » Read More
Endometriosis is one of the most challenging gynaecological conditions that primarily affects women of childbearing age. It mainly presents with pelvic pains and subfertility, causing a significant impairment in the quality of life. Unfortunately, there is no radical cure for end [....] » Read More
The United Nations Decade of Healthy Ageing (2021–2030) is a global collaboration, aligned with the last ten years of the Sustainable Development Goals, to improve the lives of older people, their families, and the communities in which they live. Among the impacts and healt [....] » Read More
Repeated embryo implantation failure (RIF) is an extremely frustrating condition for both patients and clinicians and its management constitutes a difficult challenge in the field of in vitro fertilization. There is actually no consensus in the definition and the strategy of [....] » Read More
Introduction: The intrauterine device (IUD) is a popular and effective contraception option, however, pain associated with insertion remains a chief concern for recipients as well as a barrier for obtaining an IUD. Pain localized to the gynecologic community has an extensive [....] » Read More
Background: Not only pregnancy may be associated with weakness of abdominal muscles including the Transversus Abdominis muscle but also, Cesarean delivery may contribute to this weakness. This study assessed the maximum voluntary isometric contraction (MVIC) of the core muscle; T [....] » Read More
Objective: To present an interesting case of diagnosis and management of undiagnosed dysfibrinogenemia in an otherwise uncomplicated pregnancy and its outcome. Case Report: A 29/F, G1, BMI 38kg/m2 with a previous history of surgical intervention without any bleeding or co [....] » Read More
Background: 53,000 babies are born prematurely each year in the UK. In 2021 7.6% of births are preterm, which was an increase from 7.4% in 2020. Preterm birth is a major cause of perinatal mortality. North West has introduced a preterm guideline regarding preterm Clinic. Sin [....] » Read More
From menarche at about age 12 to menopause, which may occur arguably about age 51, women have lived for about 39 years, more than a 1/3 of their lives enjoying the benefits of ovarian cycling and the hormones which such delivers: Oestrogen, Progestrogen and Testosterone. Start [....] » Read More
Objective: To compare the efficacy of intravenous and intraperitoneal injection of lidocaine and normal saline in relieving postoperative pain after elective abdominal hysterectomy. Materials and methods: For this double-blind randomized controlled study 109 patients undergoin [....] » Read More
Purpose: The initiation of this study was driven by the notable impact of uterine fibroids on Black women, who face a significantly higher risk for these benign tumors compared to other demographics. Moreover, they experience disparities in surgical outcomes, a concern that persi [....] » Read More
Background: Endometriosis is a chronic inflammatory disease that is defined by the presence of endometrial glands and stroma outside the uterine cavity. Uterine adenomyosis is the presence of ectopic endometrial tissue in the myometrium, sometimes considered a spectrum of endomet [....] » Read More
Background: Ovarian clear cell carcinoma (OCCC) is a less common subtype of epithelial ovarian cancers. It is a challenge for clinical treatment of OCCC due to the resistance to chemotherapy. In this study, we revealed the molecular landscape of ovarian clear cell carc [....] » Read More
Purpose: To analyze the contribution of magnetic resonance imaging (MRI) to the prenatal diagnosis of anomalies of brainstem structures using the example of describing our own rare clinical observations and comparing the results of MRI with the changes identified during a pr [....] » Read More
Introduction and Objectives: Our study hypothesis postulates that if patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) bladders exhibit increased inflammation, fibrosis, and urothelial dysfunction then treatment modalities that modulate inflammation and fibrosis, [....] » Read More
For many physicians, exposure to reproductive healthcare is limited based upon their chosen specialty. For this reason, it is imperative that medical students obtain a strong foundation in women’s health during their preclinical years so that they may carry this knowledge b [....] » Read More
Introduction and Objectives: Female sexual dysfunction (FSD) is a commonly associated issue in patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). FSD manifests through various abnormalities in sexual desire, arousal, orgasm, pain, distress, and satisfaction. [....] » Read More
Background: Adnexal torsion is a surgical emergency in children and adolescents and is a diagnosis that continues to stump healthcare providers. Independent predictors of torsion, both clinical and radiographic, have been identified and incorporated into a composite scoring syste [....] » Read More
Background: Prolonged waiting times in the Emergency Department have a significant psychological impact on women experiencing early pregnancy complications and possible pregnancy loss. Sheffield Teaching Hospitals operates across split sites, with the Obstetrics & Gynaec [....] » Read More
Objectives: Depression is a common mental health issue during pregnancy. Previous studies suggested a potential link between zinc and mood regulation. We aimed to investigate preconception maternal zinc intake in relation to depression during pregnancy. Methods: This secondary [....] » Read More
Objective: Although a prior history of preterm birth (PTB) is a potential risk factor for recurrence in successive pregnancies, little information is available on whether recurrence risk is modified by race/ethnicity, gestational age at birth, PTB subtypes, and interpregnancy int [....] » Read More
COVID-19 has drastically changed the experience of maternal and reproductive healthcare in the United States, amplifying existing disparities. COVID-19-related stressful birthing experiences have been associated with subsequent poor maternal and infant health outcomes including g [....] » Read More
Objective: To analyze the levels of serum vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) in patients with gestational diabetes mellitus (GDM) and their relationship with pregnancy outcome. Methods: 90 patients with GDM admitted to our hospital from January [....] » Read More
Background and objective: Placental abruption (PA) causes numerous neonatal and maternal complications and increases their mortality. However, PA might occur asymptomatically, and the diagnosis was made only when fresh or long-standing clots were detected on placental examin [....] » Read More
Introduction: Child sexual abuse (CSA) is a health emergency associated with devastating physical, behavioral, interpersonal and psychological consequences for survivors. Because children rarely disclose sexual abuse immediately, the physical examination (PE) is often delayed, an [....] » Read More
Objectives: Toxoplasma gondii is an obligatory-intracellular protozoan with variable prevalence observed worldwide. Alexandria has high Toxoplasma prevalence among pregnant females between Egyptian governorates 59.7%. Toxoplasmosis in pregnancy has variable outcomes such as misca [....] » Read More
Sickle Cell Disease (SCD) is an inherited hemoglobinopathy present in 8% of the African American population. High-risk complications include acute chest syndrome, avascular necrosis, thromboembolic events, and vaso-occlusive crises, the last of which occurs in 50% of pregnant pat [....] » Read More
Background: Gallstones acute pancreatitis has increased incidence in young women in the 2 years postpartum. Middle aged women with longer period of breastfeeding have less hospitalization for gallbladder disease. Methods: We identified all sicilian women who delivered (2013-20 [....] » Read More
Office operative hysteroscopy is an outpatient surgical procedure which can be done at hospitals, community clinic, free standing surgical centres and medical offices for treatment of uterine cavity or cervical canal pathology under direct visualization using hysteroscopic instru [....] » Read More
Vulvovaginal Congenital Anomalies affects both genital tract health as well as fertility and reproduction. External genitalia should be checked in any case immediately after delivery. Amenorrhea, oligomenorhea and pelvic pain are common symptoms of lower genital tract congenital [....] » Read More
Background: Despite the known causes of pituitary adenoma and drug induced, a high percentage of hyperprolactinemia cases remain idiopathic. Further, mechanisms of anti-prolactin autoantibody development in macroprolactinemia cases are not clearly known. Studies at whole genome l [....] » Read More
Background: There is increasing concern about the integrity of clinical research. The post-publication review process allows the assessment of potentially problematic papers after publication. The effectiveness and efficiency of post-publication assessment, which adheres to the C [....] » Read More
In Fiji, breast and cervical cancers numbers are rising steadily. Many women have fibroids, PCOS, endometriosis, uterus prolapse and other female specific illness or problems showing in younger age group of women (below 25 years). Qualitative studies conducted in the obstetrics a [....] » Read More
Metformin is a highly preferred drug that is used to treat the symptoms of polycystic ovarian syndrome among women. Pakistan is facing a continuous rise in the prevalence of polycystic ovarian syndrome. Therefore, the determination of the effectiveness of the drug in this conditi [....] » Read More
Objective: To identify whether induction of labour with Cooks Balloon increases risk of cord prolapse. Design: Retrospective case notes analysis of patients who had CAT1 CS due to cord prolapse in a district general hospital between January 2020 and December 2020 and compared [....] » Read More
India’s vision towards equitable healthcare is well known, and so are the country’s systematic efforts in the field of reproductive health and family planning (FP). However, the fifth National Family Health Survey of India (2019-21) estimated that among married women [....] » Read More
Ectopic cervical pregnancy (CP) ,is rare condition with an incidence of less than 0.1% of all pregnancies. It is associated with potentially high morbidity and mortality. In this case report of cervical pregnancy, the challenges in the diagnosis and management are discussed [....] » Read More
Infectious diseases of the female reproductive system (including bacterial vaginosis, candidiasis, viral infections, as well as vaginal dysbiosis) are one of the most common conditions that every woman faces at some point during her life. Features of the vaginal anatomy, histo [....] » Read More
Central neural block (CNB) is administered frequently for caesarean section. Post-spinal headache (PSH) is the most frequent and discomforting late complication of spinal anaesthesia.PSH is an important cause of iatrogenic maternal co-morbidity and maternal dissatisfaction. Exped [....] » Read More
Introduction: Infertility is a global public health problem; cost-effective patient-friendly treatment modalities along with psychosexual intervention strategies are essential for tobacco-mediated infertility control/prevention/management among ethnically disparate populatio [....] » Read More
Cervical cancer screening is a health intervention for women at risk of developing cervical cancer. Documented evidence shows that it is treatable if early diagnosis is made and preventable if vaccination is given at the appropriate age. Regrettably, in most developing coun [....] » Read More
Background: Intimate partner violence (IPV) in pregnant women is an important public health problem. It has a significant negative impact on the health and wellness of both the mother and her fetus. Most previous studies are more focused on IPV among non-pregnant women [....] » Read More
Infertility is defined as the inability to become pregnant after at least a year of trying. Infertility affects an estimated 10–15% of couples of reproductive age globally. The number of couples seeking infertility treatment has increased considerably in recent years as a r [....] » Read More
Title : Management of stress urinary incontinence in women with minimally invasive threads methods
Marlen Sulamanidze, Total Charm Clinic, Georgia
Introduction: Stress urinary incontinence (SUI) is a common condition affecting millions of individuals worldwide, particularly women. It occurs due to weakened pelvic floor muscles and tissues, leading to the involuntary loss of urine during activities that increase abdominal pr [....] » Read More
Title : The role of thread lifting methods in aesthetic gynecology
Ketevan Oles, APTOS, United States
Introduction: In modern medicine now its very demanded to treat and rejuvenate intimate area. Lot of methods are presented nowedays for such kind of treatments: lasers, dermal fillers, fat grafting, PRP and etc. to achieve desirable result we need to combine at least two or more [....] » Read More
Title : Using single cell transcriptomic and 3D models to study immune-endometrial-fetal interactions in physiological and pathological contexts
Ludivine Doridot, Inserm, France
In humans, for a successful reproduction, there is a need for a successful implantation of a blastocyst on the endometrial mucosa followed by the establishment of an appropriate maternal-fetal interface. Hormonal response and immune cells are recognized to induce an implantation- [....] » Read More
Title : Abnormal Embryos: Transfer impossible to disposed of
Voznesenskaya Tverdaya Julia, European Medical Center, Russian Federation
Today, IVF clinics are competing for pregnancy rates. This competition is on the rise, at clinics' websites displaying increasing figures on laboratory efficiency. This information attracts both patients and insurance companies. The most common indicator used in such reports [....] » Read More
Title : HeraHealth: Revolutionizing postpartum care through an innovative blood loss monitoring application
Aya Zaatreh, Stevens Institute of Technology, United States
Postpartum hemorrhage (PPH) poses a significant threat to maternal health, affecting 1 in 6 women during childbirth and contributing to over 20% of maternal fatalities globally. In the United States, a hemorrhaging mother is ten times more likely to die due to the reliance on a s [....] » Read More
Title : Fetal modified myocardial performance index (Mod-MPI) assessment in pregnant women with pregestational diabetes mellitus: a longitudinal prospective cohort study
Andrea Tshishimbi, Humanitas University, Italy
Background: The modified myocardial performance index (Mod-MPI) is a Doppler-based method for assessing fetal cardiac function, adapted from adult cardiology. While promising for monitoring and predicting adverse outcomes in complicated pregnancies, standardized methods, referenc [....] » Read More
Title : Features of endometrial receptivity in chronic endometritis in women with infertility
Elena Vladimirovna Kozyreva, Ulyanovsk State University, Russian Federation
The normal receptor status of the endometrium is an important factor in successful embryo implantation. The most informative methods of studying endometrial receptivity are immunohistochemical and immunocytochemical research methods. The aim of our study was to determine the rece [....] » Read More
Title : ARID1A inhibits progression of ovarian cancer by inactivating hedgehog pathway
Shouying Xu, Children's Hospital of Zhejiang University School of Medicine, China
Ovarian cancer is one kind of malignant tumors derived from epithelial and germ cells, and is the second most lethal gynecologic malignancy worldwide. The abnormal activation of the Hedgehog (Hh) pathway is crucial for cancer progression, including ovarian cancer. AT-rich interac [....] » Read More
Title : Role of biofeedback pelvic floor training in elderly patients with obstructed defecation
Mervat Sheta, Alexandria University, Egypt
Pelvic floor rehabilitation is essential to manage elderly patients with obstructed defecation. Program of biofeedback will be discussed with prerequisite, indication, and mechanism of biofeedback in these patients with usage of other physical modalities to improve emptying of [....] » Read More
Title : The impact of quercetin on oocyte maturation, gene expression in cumulus cells, and fertilization rates in a PCOS mouse model
Seyede Zahra Banihosseini, Shahid Beheshti University of Medical Sciences, Iran (Islamic Republic of)
Polycystic ovary syndrome (PCOS) is a prevalent cause of infertility in women, characterized by hyperandrogenism and oxidative stress, which negatively affect oocyte quality. In vitro maturation (IVM) is often recommended to improve oocyte quality. This study investigates the eff [....] » Read More
Title : Experience in managing a patient with breast cancer during pregnancy
Gunay Mamedbeyli, Baku Medical Plaza, Azerbaijan
Despite advancements in the diagnosis and treatment of breast cancer, malignant neoplasms are still occasionally found in pregnant women. A patient presented to our clinic at 16 weeks of gestation (second trimester). Ultrasound examination revealed a pathological mass in the left [....] » Read More
Title : The effect of cigarette smoke exposure on vitamin D levels and biochemical parameters of mothers and neonates
Seyede Zahra Banihosseini, Shahid Beheshti University of Medical Sciences, Iran (Islamic Republic of)
The primary objective of this study was to assess the impact of passive smoking during pregnancy on vitamin D levels and related biochemical indices in mothers and newborns. This research aimed to provide a comprehensive understanding of the adverse effects of cigarette smoke exp [....] » Read More
Title : Dedifferentiated mucinous ovarian carcinoma: A case report and literature review
Jasenka Mazibrada, Norfolk and Norwich university Hospital, United Kingdom
Introduction. Dedifferentiated mucinous carcinoma of the ovary is a rare, highly aggressive and molecularly distinct ovarian malignancy, characterised by frequent inactivation of core SWI/SNF complex and typically a low response rate to platinum-based standard care for& [....] » Read More
Title : Efficacy of methotrexate treatment in ectopic pregnancy: A retrospective cohort study
Swati Kumari, Bronxcare Health System, United States
Ectopic pregnancy, a potentially life-threatening condition where fertilized eggs implant and develop outside the uterus, presents considerable risks to maternal health. This retrospective cohort study, conducted at BronxCare Hospital between January 2020 and September 2022, focu [....] » Read More