Title : Prevalence and determinant factors of postpartum depression among mothers visiting postnatal and immunization clinics in selected public health institutions, Mekelle, Tigray: A hospital-based cross-sectional study
Abstract:
Objective: To assess the prevalence and determinant factors of postpartum depression among postpartum mothers who attend selected public health institutions in Mekelle, Tigray region.
Methods: This facility-based cross-sectional study was conducted among 401 postpartum mothers from January 19 to May 19, 2025. Data were collected using the Edinburgh Postnatal Depression Scale and other standardized instruments adapted to the local context. Postpartum depression was defined as an EPDS score ≥13. Data were analyzed using SPSS version 29. Variables with a p-value <0.20 in bivariate analysis were included in a multivariable logistic regression model, and factors with a p-value <0.05 were considered statistically significant predictors of postpartum depression
Results:The mean age of the participants was 28.3 ± 5.1 years. The prevalence of postpartum depression was 22.4% (n = 90; 95% CI: 18%–27%). Undesired sex of the newborn (p = 0.003), Unplanned pregnancy (p = 0.02), neonatal hospitalization (p = 0.004), poor marital satisfaction (p < 0.001), perceived poor partner support (p = 0.04), poor relationships with in-laws (p < 0.001), and intimate partner violence (p < 0.001) were independently associated with postpartum depression.
Conclusion: As the first study in Mekelle city and Tigray region to comprehensively assess postpartum depression, our findings indicate that postpartum depression is a significant public health concern, affecting nearly one in five mothers during the postpartum period. These results underscore the need for routine mental health screening, strengthened psychosocial support, and targeted interventions addressing family dynamics and intimate partner violence within maternal health services.
Key words: Postpartum depression, Prevalence ,Tigray region

